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Sheet 1 of 3 



Form PTO-1449 

INFORMATION DISCLOSURE CITATION 
IN AN APPLICATION 

(Use several sheets if necessary) 


Docket Number (Optional) 

78687-127 


Application Number 

10/428,063 


AppOetnt 

Howell etal. 


Filing Oate 

April 30. 20O3 


Group Art Unit 



U. S. Patent Documents 



EXAMINER 
INITIAL 


DOCUMENT NUMBER 


OATE 


NAME 


CLASS 


SUBCLASS 


FILING DATE 
ir MrrrlUrrliAIC 


Wo 


6,440,471 


8/27/01 


Walker ef a/. 












6 210 681 

V|b 1 W, WW 1 


4/3/01 


Walkers/ a/. 




—h 
-h 








5 912 363 


6/15/99 

W# 1 W# WW 


Naf isi-Movaahar ef a/. 












5 840 322 


1 1/24/98 


Weiss ef a/. 




-f— 








5 773 262 


6/30/98 

W# WW/ WW 


Aria a ef a/. 




f — 








5 883 678 


11/4/97 

1 1 / "T/ W f 


Heckert ef a/ 


— / 












9/23/97 

w/ w/ w r 


Franehimont ef a/ 

1 1 CM Iwl III 1 IUI 11 wi at* 


—h 












7/22/97 


Walker ef a/ 


-h 










e c/ic 17ft 
0,040, 1 / 0 




Walker flf al 

VVCMrNCl Of at. 












e ort7 ofie 
0,007,909 




rxonao ei or. 


-f— 










5,525,341 


6/11/96 


Walker etal. 












5,494,661 


2/27/96 


Tempesta 


n 










5,474,774 


12/12/95 


Walker etal. 












5,200,186 


4/6/93 


Gabetta etal. 












5,128,100 


7/7/92 


Hollis etal. 












4,857,327 


8/15/89 


Virdalm 












4,775,477 


10/4/88 


Stahl etal. 












4,698,360 


10/6/87 


Masquelier 












4,652,448 


3/24/87 


Sadowski 












4,309,207 


1/5/82 


Devlin 










/ 


4,083,779 


4/11/78 


Combe et a/. 


\ 










FOR 


EIGN PATENT DOCUMENTS 




DOCUMENT NUMBER 


DATE 


COUNTRY 


CLASS 


SUBCLASS 




YES 


NO 


"Yd 


WO 96/30033 


10/3/96 


WIPO 




9- 










WO 96/28135 


9/19/96 


WIPO 












V 


WO 95726197 


10/5/95 


WIPO 











OTHER DOCUMENTS (Including Author, Title, Date, Pertinent Pages, Etc.) 



Ahuja etal. (1998) "Loss of fimbrial adhesion with the addition of Vaccinium macrocarpon 
to the growth medium of P-fimbriated Escherichia coir J.Urol. 159:559-562. 



Avom etal. (1994) "Reduction of bacteriuria and pyuria after ingestion of cranberry juice" 

JAMA 271 (10):751 -754. 

Bahorun et al. (1996) M Oxygen species scavenging activity of phenolic extracts from 
hawthorn fresh plant organs and pharmaceutical preparations", Arzneimittelforschung 
46(11):1086-9. 



i 



Boms r et al, (1996) Vn Vitro anticancer activity of fruit extracts for Vaccinium species" 
Planta Medica 62(3):212-216. 



f 


O 




Marwan and Nag 1 (1 986) "Characterization of cranberry benzoates and their 

ontiminrnhiat nmnortiAQ 0 1 Fnftd Sel 51/4)1069*1070 

aniirnicruuiai prupoiuuo w. ruuu ow. %ji\*t/ iuwj*iv»v, 








Morimoto etal. (1988) Tannins and related compounds. Isolation and characterization of 
proaninocyanioins wnn a oouDiy*iini\eu unu irorn vacciniurn vius m iuaea l. wiium* rueum. 
Bull. 36(1):33-38. 








UT6K &I 31. 11 99 11 r\nu~CSCnBncnia CUM ttUiiooiun auuvuy ui Lriaiiuoiiy cuiu uiueuouy 

juices* N. Engl. J. Med. 324:1599. 








n Ar *. p CfniMiirA on/4 PkAmS/*ol PrnnoHioc nf tho f^nnHonQoH Tannine in Plant 

rOiisr, wiriiCiure ano wnernicai r rapoiuoo ui mo vuiiuoiideu i aiiiinio, hi nai u 
Polvohenols. (Hemingway & Laks eds., 1992), pp.245-256. 








Porter. Flavans and Proanthocvanidins. in Flavonoids: Advances in Research Since 
1986. (Harboume ed.. 1994) pp.23-25. 








Rakotoarison et at. (1997) 'Antioxidant activities of polyphenols extracts from flowers, in 
vitro callus and cell suspension cultures of Crataegus monogyna" Pharmazie 52(1):60-4. 








Scalbert (1991) "Antimicrobial properties of tannins" Phytochemistry 30(12):3874-3883. 








Schilling era/. (1973) o-NMn-opeKirosKopiscne rvonsuiuiionsermiuiung aer v/3o n 24^i2 
Procyanidine" Liebigs Ann. Chem. 9:1471-1475. 








oCnmiut anO oODOta [ lyoo) An examination OT uie anu-aanerence acuvuy 01 granucrry 

juice on urinary and nonurinary bacterial isolates" Microbios. 55:173-181. 








ohanat et al. (1 996) Anu-compiimeniary aciivuy of oraraegus sinaica , riania. ivieu. 
62(1):10-3. 








Sobota (1984) "Inhibition of bacterial adherence by cranberry juice: Potential use for the 
treatment of unnary tract infections j.uroi. 101 .iuid-iuio. 








Swain and Hillis (1959) "The phenolic constituents of Prunus domestic* J. Sci. Food 
Agnc. 10:63-68. 








Thompson etal. (1972) "Plant Proanthocyanidins. Part I. Introduction: Isolation, 
structure, and distnbution in nature ot plant procyanioins j. unem ooc., rerKin .1 rans. 
1:1387-1399. 








Wang etal. (1978) "Isolation and characterization of polyphenol compounds in 
cranberries" J. Food Sci. 43(5):1402-1404. 




/ 




Wang etal. (1996) "Differential inhibition of eukaryote protein kinases by condensed 
tannins" Phytochemistry 43(2):359-365. 








Vyeino0s119t1) "Kpnsffttoic 


!49fe64. hJnJr Jrtos/arf? J 








Phy^Chim. D*bf£cina 172 






Williams etal. (1983) "Molecular weight profiles of proanthocyanldin polymers" 
Phytochemistry 22(2):569-572. 


-i 


/ 




Zafriri etal. (1989) "Inhibitory activity of cranberry juice on adherence of Type 1 and Type 
P fimbriated Escherichia coli to eukaryotic cells." Antimicrobial Agents and Chemotherapy 
1:92-98. 


EXAM 


^T- ft- Q/ch 


OATE CONSIDERED 


EXAMINER: Initial if citation considered, whether or not citation is in conformance with MPEP « 609; Draw line through 
citation if not in conformance and not considered Include copy with next communication to applicant 



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Sheet 3 of 3 



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